Gangrene

Gangrene is a serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies (necrosis).^[1][2] This may occur after an injury or infection, or in people suffering from any chronic health problem affecting blood circulation.^[2] The primary cause of gangrene is reduced blood supply to the affected tissues, which results in cell death.^[3] Diabetes and long-term smoking increase the risk of suffering from gangrene.^[2][3]